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Monthly Update Report for Trials Started in December 2025


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1: Summary data from new trials identified for Thyroid Cancer.


Overview

Number of Trials: 1

This trial evaluates lavender aromatherapy versus placebo for reducing anxiety and pain in adults undergoing awake outpatient otolaryngologic procedures. It targets patients not on recent pain or psychotropic medications.

Common Criteria Across Trials

Common Inclusion

  • Adults 18 years or older
  • Undergoing awake otolaryngologic procedures in outpatient clinic
  • Able to provide informed consent

Common Exclusion

  • Hypersensitivity to fragrances
  • Systemic NSAIDs or pain medications within 48 hours
  • Regular use of anxiolytics, hypnotics, sedating antihistamines, or antidepressants within 4 weeks
  • Pregnant or breastfeeding
  • Participation in another clinical trial within 30 days

2: Extracted Trials with New Information


Trials with Special Criteria

Unique or Unusual Criteria

Trials with Emerging Treatments


3: Individual Trial Overviews


NCT07299474

Efficacy Of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures

Organization/Sponsor: Cedars-Sinai Medical Center


Example patient: A 45-year-old non-pregnant adult undergoing an awake thyroid biopsy in the outpatient clinic who has not taken pain medications or antidepressants recently and has no fragrance allergies.

Phase N/A

Interventions

  • Aromatherapy: Placebo Aromatherapy
    Summary: An inactive substance providing baseline measurements for experimental protocol comparison (NCI Thesaurus).
  • Aromatherapy: Lavender Aromatherapy
    Summary: Essential oil from Lavandula flowers used for aromatic properties in aromatherapy to reduce anxiety and pain (NCI Thesaurus).

Key Inclusion

  • Adults ≥18 years old
  • Undergoing awake otolaryngologic procedures
  • Outpatient clinic setting
  • Able to provide informed consent

Key Exclusion

  • Hypersensitivity to fragrances
  • Systemic NSAIDs or pain medications within 48 hours
  • Anxiolytics, hypnotics, sedating antihistamines, or antidepressants within 4 weeks
  • Pregnant or breastfeeding
  • Participation in another clinical study within 30 days